Contrast mechanisms associated with neuromelanin-MRI
نویسندگان
چکیده
منابع مشابه
The Neuromelanin-related T2* Contrast in Postmortem Human Substantia Nigra with 7T MRI
High field magnetic resonance imaging (MRI)-based delineation of the substantia nigra (SN) and visualization of its inner cellular organization are promising methods for the evaluation of morphological changes associated with neurodegenerative diseases; however, corresponding MR contrasts must be matched and validated with quantitative histological information. Slices from two postmortem SN sam...
متن کاملMRI with hepatobiliary contrast
Hepatobiliary contrast agents currently are essentially gadolinium based agents (Gd-EOB-DTPA and GdBOPTA) with dual ability to perform dynamic contrast enhanced imaging similar to extracellular gadolinium contrast as well as providing hepatobiliary uptake and excretion in later phases. Hepatobiliary uptake and excretion with gadoxetic acid (Gd-EOB-DTPA) is related to OATP and cMOAT and MRP2 rec...
متن کاملBiophysical mechanisms of phase contrast in gradient echo MRI.
Recently reported contrast in phase images of human and animal brains obtained with gradient-recalled echo MRI holds great promise for the in vivo study of biological tissue structure with substantially improved resolution. Herein we investigate the origins of this contrast and demonstrate that it depends on the tissue "magnetic architecture" at the subcellular and cellular levels. This archite...
متن کاملBiophysical mechanisms of MRI signal frequency contrast in multiple sclerosis.
Phase images obtained with gradient echo MRI provide image contrast distinct from T1- and T2-weighted images. It is commonly assumed that the local contribution to MRI signal phase directly relates to local bulk tissue magnetic susceptibility. Here, we use Maxwell's equations and Monte Carlo simulations to provide theoretical background to the hypothesis that the local contribution to MRI signa...
متن کاملA new approach to contrast enhancement in MAGICA gel dosimeter image with MRI technique
parameters that have to be measured in gel dosimetry. However, the resolution in gel is strongly dependant on gel composition. Selection of optimum method in dose response readout and proper values of parameters can result in noise reduction as well as improvement of contrast, and spatial resolution considerably. Materials and Methods: MAGICA polymer gel dosimeters were manufactured and irradia...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2016
ISSN: 0740-3194
DOI: 10.1002/mrm.26584